TDM
Therapeutic drug monitoring
Evidence for appropriate monitoring, concentration-guided dosing and clinically meaningful outcomes.
CAPTURE / Clinical Pharmacology
Better evidence for safer, more effective use of medicines.
Explore clinical pharmacology, precision therapeutics, drug safety, pharmacogenomics and therapeutic drug monitoring evidence.
PRECISION THERAPEUTICS
Clinical pharmacology as a bridge between mechanisms and outcomes.
Medicines are used in patients, not in isolation. Dose, exposure, response, genetics and clinical context can each matter.
PGx
Pharmacogenomics
Evidence for the value and appropriate use of genetic testing to inform drug therapy.
PK / PD
Pharmacokinetics & pharmacodynamics
Interpreting exposure–response evidence and its connection to therapeutic benefits and harms.
SAFETY
Drug safety & adverse reactions
Assessment of adverse drug events, causal attribution and the certainty of benefit–harm evidence.
PHARMACOTHERAPY
The broader question is better use of medicines.
Our interests extend beyond tests and monitoring to clinically important pharmacotherapy decisions.
Decisions across the care pathway
Questions may involve who should receive a treatment, how treatment should be selected or adjusted, how benefits and harms should be weighed, and when additional testing or monitoring is justified.
We are particularly interested in integrating randomized evidence with observational, PK/PD, PGx and real-world research where appropriate.